Gut Microbiota and Neuro Diseases

Changes in gut microbiota are linked with the pathogenesis of gastrointestinal and neuro diseases. Creative Biolabs is dedicated to providing the highest level of service to support gut microbiota and neuro diseases research. Our experienced scientists provide fully integrated end-to-end solutions for your projects.

Gut-Brain Axis and Neuro Diseases

The gut microbiota influences the health of its host by providing crucial benefits in the form of immune system development, prevention of infections, nutrient acquisition, and maintaining brain and nervous system functionality. Once the gut microbiota disorder occurs, the structure and function of the intestinal flora will change. The dysregulation of gut microbiota contributes to brain disorders, including cognitive dysfunction, neurodegeneration, and cerebrovascular diseases. In brain disorders, gut dysbiosis is involved in neuropsychiatric manifestations, including autism spectrum disorder, anxiety, and depression by interfering with neurotransmitter homeostasis, and neurodegenerative diseases, such as Alzheimer’s disease and Parkinson’s disease by releasing abnormal metabolites from the gut.

Dysregulation of the gut microbiota in brain disorders. Fig.1 Dysregulation of the gut microbiota in brain disorders. (Zhu, 2020)

Our Services

Human-associated microbiology now clearly extends beyond infectious and gastrointestinal diseases to areas barely imaginable a few decades ago, including metabolism, neoplasia, and central nervous system function. We keep an eye on the latest scientific findings worldwide and our scientists focus on the goal of understanding microbiomes. Creative Biolabs provides a versatile platform to characterize the relationship between gut microbiota and neuro diseases. With extensive experience, we are committed to being your good partner to assist your project efficiently and cost-effectively. We provide the following services but are not limited to them. Any other specific requirements, please feel free to contact us to learn more.

Our Guarantees

To better understand the links between gut microbiota and the brain, Creative Biolabs provides a wide range of services, including animal model construction, tumor assessment, neurotransmitters/cytokine measurement, etc. Equipped with state-of-the-art equipment and platforms, our scientists support your gut microbiota projects using many approaches including next-generation sequencing techniques, multi-omics approaches, and related bioassays. We are fully committed to contributing to the success of your projects and creating reliable and trusted partnerships. Please don’t hesitate to contact us for more information.

Reference

  1. Zhu, S.; et al. The progress of gut microbiome research related to brain disorders. Journal of neuroinflammation, 2020, 17(1): 1-20.

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