Hbl-2 In Vitro Anti-Tumor Efficacy Assay

This assay is to provide Hbl-2-based In Vitro Anti-Tumor Efficacy Assay to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.

Hbl-2

Human

The HBL-2 cell line is derived from an AIDS-SNCCL (AIDS-associated small non-cleaved cell lymphoma) patient. After immunophenotypic and molecular genetic analysis, the HBL-2 was established from the original tumor clones. The HBL-2 cell line presents surface immunoglobulin and B-cell restricted markers as well as a phenotype consistent with SNCCL; the cell line also displays clonal immunoglobulin gene rearrangement. The HBL-2 cell line is considered useful as a biological model to study AIDS-associated non-Hodgkin lymphomagenesis (AIDS-NHL) and the impacts of biological, immunological, and viral factors involved.

Mantle Cell Lymphoma; MCL

Oncology

In Vitro Anti-Tumor Efficacy Assay

Tumor-derived cell lines have been the mainstay for anti-cancer drug discovery, and the assessment of in vitro efficacy is a common method to evaluate the anti-cancer efficacy with various kinds of therapeutic candidates.

Oncology Efficacy Assays