Hbl-2 In Vitro Real-time Cell Proliferation Monitoring and Live Cell Imaging Assay (Cell Proliferation)
CAT#: ITS-0123-YF3595
Target Cell Organism: Human
Target Cell Name: Hbl-2
Assay Type: Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Overview
This assay is to provide Hbl-2-based In Vitro Real-time Cell Proliferation Monitoring and Live Cell Imaging Assay (Cell Proliferation) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
Hbl-2
Target Cell Organism
Human
Target Cell Background
The HBL-2 cell line is derived from an AIDS-SNCCL (AIDS-associated small non-cleaved cell lymphoma) patient. After immunophenotypic and molecular genetic analysis, the HBL-2 was established from the original tumor clones. The HBL-2 cell line presents surface immunoglobulin and B-cell restricted markers as well as a phenotype consistent with SNCCL; the cell line also displays clonal immunoglobulin gene rearrangement. The HBL-2 cell line is considered useful as a biological model to study AIDS-associated non-Hodgkin lymphomagenesis (AIDS-NHL) and the impacts of biological, immunological, and viral factors involved.
Related Diseases
Mantle Cell Lymphoma; MCL
Research Area
Oncology
Assay Name
In Vitro Real-time Cell Proliferation Monitoring and Live Cell Imaging Assay (Cell Proliferation)
Assay Description
The live imaging assays can monitor cancer cell proliferation as well as distinguish cells undergoing apoptosis and necrosis.
Assay Type
Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Type Details
Uncontrolled proliferation is one of the main features of cancer cells. Cell-based in vitro assays are employed to determine whether test molecules possess direct cytotoxic/antiproliferative effects in cancer cells.