HCT116 In Vitro 7-Aminoactinomycin D Assay (Cell Viability)

CAT#: ITS-1022-YF963
Target Cell Organism: Human
Target Cell Alternative Name: HCT 116
Target Cell Name: HCT116
Assay Type: Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Overview
This assay is to provide HCT116-based In Vitro 7-Aminoactinomycin D Assay (Cell Viability) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
HCT116
Target Cell Organism
Human
Target Cell Background
HCT 116 cell line was isolated from the colon of an adult male with colon cancer. It has a mutation in codon 13 of the ras proto-oncogene and can be d as a positive control for PCR assays of mutation in this codon.
Target Cell Alternative Name
HCT 116
Related Diseases
Colon Cancer
Research Area
Oncology
Assay Name
In Vitro 7-Aminoactinomycin D Assay (Cell Viability)
Short Description
HCT116-cell based In Vitro 7-Aminoactinomycin D Assay (Cell Viability)
Assay Description
7-Aminoactinomycin D is a fluorescent dye that can also be used to detect viable/non-viable cells (excluded by viable cells) by fluorescence microscopy and FCM.
Assay Type
Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Type Details
Uncontrolled proliferation is one of the main features of cancer cells. Cell-based in vitro assays are employed to determine whether test molecules possess direct cytotoxic/antiproliferative effects in cancer cells.
Assay Subtype
Cell Viability Assay
Assay MOA
Dye Exclusion Assays
For Research Use Only | Not For Clinical Use
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