HEL 92.1.7 In Vitro ABTS Radical Cation Decolorization Assay (Oxidative Stress)

CAT#: ITS-1122-YF1548
Target Cell Organism: Human
Target Cell Name: HEL 92.1.7
Assay Type: Oxidative Stress Assays
Assay Overview
This assay is to provide HEL 92.1.7-based In Vitro ABTS Radical Cation Decolorization Assay (Oxidative Stress) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
HEL 92.1.7
Target Cell Organism
Human
Target Cell Background
HEL 92.1.7 is a erythroblast cell line isolated from the bone marrow of a 30-year-old, White, male patient with erthroleukemia. This cell line can be used in immune system disorder research and immunology research.
Related Diseases
Erythroleukemia
Research Area
Oncology
Assay Name
In Vitro ABTS Radical Cation Decolorization Assay (Oxidative Stress)
Short Description
HEL 92.1.7-cell based In Vitro ABTS Radical Cation Decolorization Assay (Oxidative Stress)
Assay Description
It's a commonly used simple antioxidant assay. The ability of antioxidants to reduce ABTS free radical (ABTS.) to ABTS is measured in the ABTS assay.
Assay Type
Oxidative Stress Assays
Assay Type Details
Disturbance between the production of reactive oxygen species (ROS), free radicals and antioxidant mechanisms is defined as the oxidative stress, or more precisely, it is an imbalance between the oxidant and antioxidant state in cells. This imbalance can cause harmful effects to cells and biomolecules, which ultimately causes adverse effects in the whole organism. Oxidative imbalance can target important proteinsand lipids in cells, which can increase the risk of developing a cancer. On the other hand, increased ROS production in cancer cells by certain cancer drugs can also arrest cancer cell cycle and cause senescence and apoptosis through oxidative stress.
Assay Subtype
Antioxidant Assay
For Research Use Only | Not For Clinical Use
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