Hep 3B In Vitro Glutathione Assay (Oxidative Stress)

CAT#: ITS-1022-YF2170
Target Cell Organism: Human
Target Cell Alternative Name: Hep-3B; Hep3B; Hep 3B2.1-7
Target Cell Name: Hep 3B
Assay Type: Oxidative Stress Assays
Assay Overview
This assay is to provide Hep 3B-based In Vitro Glutathione Assay (Oxidative Stress) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
Hep 3B
Target Cell Organism
Human
Target Cell Background
Hep 3B is a cell line exhibiting epithelial morphology that was isolated from liver tissue derived from an 8-year-old, Black youth with liver cancer. This cell line contains an integrated hepatitis B virus genome.
Target Cell Alternative Name
Hep-3B; Hep3B; Hep 3B2.1-7
Related Diseases
Hepatocellular Carcinoma
Research Area
Oncology
Assay Name
In Vitro Glutathione Assay (Oxidative Stress)
Short Description
Hep 3B-cell based In Vitro Glutathione Assay (Oxidative Stress)
Assay Type
Oxidative Stress Assays
Assay Type Details
Disturbance between the production of reactive oxygen species (ROS), free radicals and antioxidant mechanisms is defined as the oxidative stress, or more precisely, it is an imbalance between the oxidant and antioxidant state in cells. This imbalance can cause harmful effects to cells and biomolecules, which ultimately causes adverse effects in the whole organism. Oxidative imbalance can target important proteinsand lipids in cells, which can increase the risk of developing a cancer. On the other hand, increased ROS production in cancer cells by certain cancer drugs can also arrest cancer cell cycle and cause senescence and apoptosis through oxidative stress.
Assay Subtype
Markers Thiobarbituric Acid Reactive Substances
For Research Use Only | Not For Clinical Use
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