HepG2 In Vitro Boyden Chamber Assay (Angiogenesis)
CAT#: ITS-1022-YF1209
Target Cell Organism: Human
Target Cell Alternative Name: Hep G2
Target Cell Name: HepG2
Assay Type: Angiogenesis Monitoring Assays
Assay Overview
This assay is to provide HepG2-based In Vitro Boyden Chamber Assay (Angiogenesis) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
HepG2
Target Cell Organism
Human
Target Cell Background
Hep G2 is an immortal cell line which was derived in 1975 from the liver tissue of a 15-year-old Caucasian male from Argentina with a well-differentiated hepatocellular carcinoma. These cells are epithelial in morphology, have a modal chromosome number of 55, and are not tumorigenic in nude mice.
Target Cell Alternative Name
Hep G2
Related Diseases
Hepatocellular Carcinoma
Research Area
Oncology
Assay Name
In Vitro Boyden Chamber Assay (Angiogenesis)
Short Description
HepG2-cell based In Vitro Boyden Chamber Assay (Angiogenesis)
Assay Description
The Boyden chamber assay has been used to study angiogenesis by assessing endothelial cell migration.
Assay Type
Angiogenesis Monitoring Assays
Assay Type Details
Local and regional metastasis is a life-threatening condition in cancer, which is hard to control with the available cancer treatment options. In metastasis, cancer cells move away from primary tumors and travel through the blood and lymphatic system and form new tumors on other parts. A vascular network growth is important for cancer metastasis. Angiogenesis is a process that is known as the formation of new blood vessels with the help of existing blood vessels and angiogenesis has been reported to play a major role in cancer growth and metastasis. Tumors can send chemical signals to nearby normal tissues to stimulate angiogenesis. New blood vessels can feed growing tumors with nutrients and oxygen, allowing cancer cells to spread (metastasis).