HMGCR-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR157
Cell Type: CD8 T Cells
RNA writers: METTL3
RNA readers: YTHDF1
RNA erasers: FTO
Enzymes: SIRT1
RNA types: mRNAs
Modification: ψ
RNA editing: C to U
Short Description
This product is a HMGCR-targeted RNA modification and metabolomics analysis tool based on the ψ (METTL3-YTHDF1-FTO-SIRT1-BHQ2) modification and TCA cycle-mediated (hnRNPs-Acetyl-CoA-ADP) metabolic analysis system.
RNA writers
METTL3
RNA readers
YTHDF1
RNA erasers
FTO
Enzymes
SIRT1
RNA types
mRNAs
Modification
ψ
Label
BHQ2
RNA editing
C to U
Cell Type
CD8 T Cells
Oligonucleotide
2'-H
RNA Construction
mRNAs-ψ-METTL3-YTHDF1-FTO-SIRT1-BHQ2
Substrates
Acetyl-CoA
Cofactors
ADP
Pathway
TCA cycle
Epigenetic regulator
SIRT6 deficiency
Metabolic alteration
Upregulating glycolysis
Targeting diseases
Acute Myeloid Leukemia
RNA-binding proteins
hnRNPs
Metabolic Reprogramming
TCA cycle-hnRNPs-Acetyl-CoA-ADP
Target
HMGCR
Alternative Names
HMGCR; HMG-CoA reductase; Entrez 3156; LDLCQ3; 3-hydroxy-3-methylglutaryl-CoA reductase; Hydroxymethylglutaryl-CoA reductase
Gene ID
3156(Human); 15357(Mouse); 25675(Rat)
UniProt ID
P04035(Human); Q01237(Mouse); P51639(Rat)
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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