HSP27-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR64
Cell Type: M1 macrophages
RNA writers: METTL3
RNA readers: YTHDF1
RNA erasers: FTO
Enzymes: NNMT
RNA types: mRNAs
Modification: ψ
RNA editing: T to C
Short Description
This product is a HSP27-targeted RNA modification and metabolomics analysis tool based on the ψ (METTL3-YTHDF1-FTO-NNMT-phos) modification and Glycolysis-mediated (RBFOX3-Lactyl-CoA-NAD+) metabolic analysis system.
RNA writers
METTL3
RNA readers
YTHDF1
RNA erasers
FTO
Enzymes
NNMT
RNA types
mRNAs
Modification
ψ
Label
phos
RNA editing
T to C
Cell Type
M1 macrophages
Oligonucleotide
Undisclosed, GalNac
RNA Construction
mRNAs-ψ-METTL3-YTHDF1-FTO-NNMT-phos
Substrates
Lactyl-CoA
Cofactors
NAD+
Pathway
Glycolysis
Epigenetic regulator
ARID1A deficiency
Metabolic alteration
Upregulating glutamine metabolism
Targeting diseases
Adrenocortical carcinoma
RNA-binding proteins
RBFOX3
Metabolic Reprogramming
Glycolysis-RBFOX3-Lactyl-CoA-NAD+
Target
HSP27
Alternative Names
HSPB1; CMT2F; HEL-S-102; HMN2B; HS.76067; HSP27; HSP28; Hsp25; SRP27; heat shock protein family B (small) member 1
Gene ID
3315(Human); 15507(Mouse); 24471(Rat)
UniProt ID
P04792(Human); P14602(Mouse); P42930(Rat)
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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