Human CD226 ELISA Kit, Lot 21AO-1249 [Cancer Immune Checkpoint Assay Kit]

CAT#: IOK-05-P1160
Product Type: ELISA Kit
Target: CD226
Short Description
The kit is designed for in vitro quantitative measurement of Human CD226 in Plasma, Tissue Samples.
Description
Quantitative measurement of CD226 in serum, plasma, tissue homogenates and other biological fluids.
Applications
ELISA
Target
CD226
Reactivity
Human
Detection Method
Colorimetric
Method Type
Sandwich ELISA
Analytical Method
Quantitative
Sample Type
Plasma, Tissue Samples
Cross-Reactivity
No significant cross-reactivity or interference was observed.
Components
Micro ELISA Plate
Lyophilized Standard
Sample / Standard dilution buffer
Biotin- detection antibody (Concentrated)
Antibody dilution buffer
HRP-Streptavidin Conjugate (SABC)
SABC dilution buffer
TMB substrate
Stop Solution
Wash buffer (25X)
Plate sealers
Sensitivity
< 0.094 ng/mL
Plate
Pre-coated
Assay Precision
Intra-Assay: CV < 8%, Inter-Assay: CV < 10%
Storage
4 °C
Expiry Date
6 months
Restrictions
For Research Use only
Alternative Name
Cluster Of Differentiation 226 (CD226)
Synonyms
CD226; cd226; zgc:158817; BC051526; DNAM-1; DNAM1; Pta1; TLiSA1; PTA1; CD226 molecule; CD226 antigen; CD226; cd226; Cd226
Background
CD226 involves in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell. Cell surface receptor for NECTIN2. Upon ligand binding, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Competes with PVRIG for NECTIN2-binding.
Gene ID
10666
UniProt
Q15762
Pathways
Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
For Research Use Only | Not For Clinical Use
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