Human IL12 ELISA Kit, Lot 21AO-695 [Cancer Immune Checkpoint Assay Kit]

CAT#: IOK-05-P606
Product Type: ELISA Kit
Target: IL12
Short Description
The kit is designed for in vitro quantitative measurement of Human IL12 in Cell Culture Supernatant, Serum, Plasma (heparin), Plasma (citrate), Plasma (EDTA).
Applications
ELISA
Application Notes
Detection Wavelength: 450 nm
Target
IL12
Reactivity
Human
Detection Method
Colorimetric
Method Type
Sandwich ELISA
Analytical Method
Quantitative
Sample Type
Cell Culture Supernatant, Serum, Plasma (heparin), Plasma (citrate), Plasma (EDTA)
Specificity
Natural and recombinant Human IL-12p70 Ligand.
Material not included
Microplate reader.
Pipettes and pipette tips.
EP tube Deionized or distilled water.
Sensitivity
7 pg/mL
Sample Volume
20 μL
Assay Time
3 h
Plate
Pre-coated
Storage
4 °C
Restrictions
For Research Use only
Alternative Name
Interleukin 12
Synonyms
CLMF; CLMF2; IL-12B; NKSF; NKSF2; p40; Il-12b; Il12p40; Il-12p40; Il12; IL-12p40; IL-12; LOC100217488; IL-12p35; Il-12a; Ll12a; p35; IL12p40; IL12B; IL-12 p35; interleukin 12B; interleukin 12A; interleukin 12b; interleukin 12a; Interleukin 12 level; IL12B; IL12A; Il12b; Il12a; IL12; il12a
Background
IL-12, also known as natural killer cell stimulatory factor (NKSF) or cytotoxic lymphocyte maturation factor (CLMF), is a pleiotropic cytokine produced primarily by antigen-presenting cells (monocytes/macrophages, dendritic cells and B lymphocytes). IL-12 has multiple effects on T lymphocytes and natural killer (NK) cells, including the ability to stimulate cytotoxicity, proliferation, cytokine production and Th1 subset development (1, 2).IL-12 is a disulfide-linked, 70 kDa (p70) heterodimeric glycoprotein composed of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit.
Gene ID
3592
UniProt
P29459
Pathways
JAK-STAT Signaling, TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
For Research Use Only | Not For Clinical Use
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