Human IL12 ELISA Kit, Lot 21AO-695 [Cancer Immune Checkpoint Assay Kit]
CAT#: IOK-05-P606
Product Type: ELISA Kit
Target: IL12
Short Description
The kit is designed for in vitro quantitative measurement of Human IL12 in Cell Culture Supernatant, Serum, Plasma (heparin), Plasma (citrate), Plasma (EDTA).
IL-12, also known as natural killer cell stimulatory factor (NKSF) or cytotoxic lymphocyte maturation factor (CLMF), is a pleiotropic cytokine produced primarily by antigen-presenting cells (monocytes/macrophages, dendritic cells and B lymphocytes). IL-12 has multiple effects on T lymphocytes and natural killer (NK) cells, including the ability to stimulate cytotoxicity, proliferation, cytokine production and Th1 subset development (1, 2).IL-12 is a disulfide-linked, 70 kDa (p70) heterodimeric glycoprotein composed of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit.
Gene ID
3592
UniProt
P29459
Pathways
JAK-STAT Signaling, TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome