Human LAG3 ELISA Kit, Lot 21AO-164 [Cancer Immune Checkpoint Assay Kit]

CAT#: IOK-05-P075
Product Type: ELISA Kit
Target: LAG3
Short Description
The kit is designed for in vitro quantitative measurement of Human LAG3 in Plasma, Tissue Samples.
Description
Quantitative measurement of LAG3 in serum, plasma, tissue homogenates and other biological fluids.
Applications
ELISA
Application Notes
Quantitative measurement of LAG3 in human serum, plasma, tissue homogenates and other biological fluids.
Comment
Further details regarding sample type: Serum, plasma, tissue homogenates and other biological fluids.Absorbance (450 nm)
Target
LAG3
Reactivity
Human
Detection Method
Colorimetric
Method Type
Sandwich ELISA
Analytical Method
Quantitative
Sample Type
Plasma, Tissue Samples
Components
Micro ELISA Plate
Lyophilized Standard
Sample / Standard dilution buffer
Biotin- detection antibody (Concentrated)
Antibody dilution buffer
HRP-Streptavidin Conjugate (SABC)
SABC dilution buffer
TMB substrate
Stop Solution
Wash buffer (25X)
Plate sealers
Sensitivity
< 46.875 pg/mL
Plate
Pre-coated
Assay Precision
Intra-Assay: CV < 8%, Inter-Assay: CV < 10%
Storage
4 °C
Expiry Date
6 months
Restrictions
For Research Use only
Alternative Name
Lymphocyte Activation Gene 3 (LAG3)
Synonyms
CD223; LAG-3; Ly66; lymphocyte activating 3; lymphocyte-activation gene 3; LAG3; Lag3
Background
Lymphocyte-activation gene 3 (LAG3) is a cell surface molecule with diverse biologic effects on T cell function. LAG3's main ligand is MHC class II, to which it binds with higher affinity than CD4. The protein negatively regulates cellular proliferation, activation, and homeostasis of T cells, in a similar fashion to CTLA-4 and PD-1 and has been reported to play a role in Treg suppressive function.
Gene ID
3902
UniProt
P18627
Pathways
Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
For Research Use Only | Not For Clinical Use
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