Human Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) ELISA Kit, Lot 21AO-231 [Cancer Immune Checkpoint Assay Kit] (CAT#: IOK-05-P142)

Microplate: 96 wells
Lyophilized Standard
Sample / Standard dilution buffer
Biotin- detection antibody (Concentrated)
Antibody dilution buffer
HRP-Streptavidin Conjugate (SABC)
SABC dilution buffer
TMB substrate
Stop Solution
Wash buffer (25X)
Plate sealers

Pre-coated

4 °C

6 months

For Research Use only

GITR Ligand

Gitrl; AITRL; GITRL; TL6; hGITRL; TNLG2A; tumor necrosis factor (ligand) superfamily; member 18; TNF superfamily member 18; Tnfsf18; TNFSF18

Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1. Promotes leukocyte adhesion to endothelial cells. Regulates migration of monocytes from the splenic reservoir to sites of inflammation.

8995

Q9UNG2