Human Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) ELISA Kit, Lot 21AO-231 [Cancer Immune Checkpoint Assay Kit]

CAT#: IOK-05-P142
Product Type: ELISA Kit
Target: Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18)
Short Description
The kit is designed for in vitro quantitative measurement of Human Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) in Plasma, Serum, Tissue Samples.
Description
Quantitative measurement of TNFSF18 in human serum, plasma, tissue homogenates and other biological fluids.
Applications
ELISA
Application Notes
Quantitative measurement of TNFSF18 in human serum, plasma, tissue homogenates and other biological fluids.
Comment
Further details regarding sample type: Human serum, plasma, tissue homogenates and other biological fluids.
Target
Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18)
Reactivity
Human
Detection Method
Colorimetric
Method Type
Sandwich ELISA
Analytical Method
Quantitative
Sample Type
Plasma, Serum, Tissue Samples
Components
Microplate: 96 wells
Lyophilized Standard
Sample / Standard dilution buffer
Biotin- detection antibody (Concentrated)
Antibody dilution buffer
HRP-Streptavidin Conjugate (SABC)
SABC dilution buffer
TMB substrate
Stop Solution
Wash buffer (25X)
Plate sealers
Plate
Pre-coated
Storage
4 °C
Expiry Date
6 months
Restrictions
For Research Use only
Alternative Name
GITR Ligand
Synonyms
Gitrl; AITRL; GITRL; TL6; hGITRL; TNLG2A; tumor necrosis factor (ligand) superfamily; member 18; TNF superfamily member 18; Tnfsf18; TNFSF18
Background
Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1. Promotes leukocyte adhesion to endothelial cells. Regulates migration of monocytes from the splenic reservoir to sites of inflammation.
Gene ID
8995
UniProt
Q9UNG2
For Research Use Only | Not For Clinical Use
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