PharmaOnco™ BMS 493

CAT#: ITS-0622-YT342
Product Type: Small Molecules
Species: Human, Mouse, Rat, Non-Human Primate, Other
Product Overview
BMS 493 is a pan-retinoic acid receptor (pan-RAR) inverse agonist. This compound has been shown to increase nuclear corepressor (NCoR) interaction with RARs. RAR controls a number of physiological processes including cell growth, differentiation, survival, and death.
Applications
Inverse Agonist of pan-RAR, Cell Expansion and Differentiation
Size
1mg
Chemical Name
4-[(1E)-2-[5,6-Dihydro-5,5-dimethyl-8-(2-phenylethynyl)-2-naphthalenyl]ethenyl]benzoic acid
Cell Type
Airway Cells, Cancer Cells and Cell Lines, Hematopoietic Stem and Progenitor Cells, Monocytes
Species
Human, Mouse, Rat, Non-Human Primate, Other
Pathway
Retinoid
Area of Interest
Immunology, Infectious Diseases,Cancer, Gene therapy
Limitation
Restrictions for research use only. Intended for use by laboratory professionals.
Sterility
Sterile
Shelf Life
Stable for 12 months from date of manufacture on label. Do not use past expiration date.
Storage
Store at -20°C. Avoid exposure to light.
Molecular Weight
404.5 g/mol
Format
A crystalline solid
Reconstitution
For 10 mM stock solution in DMSO, resuspend 1 mg in 247 μL of DMSO.
For Research Use Only | Not For Clinical Use
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