PharmaOnco™ CH223191

CAT#: ITS-0622-YT336
Product Type: Small Molecules
Product Overview
CH-223191 is a potent and specific antagonist of aryl hydrocarbon receptor (AhR) (IC50 = 30 nM). It blocks TCDD-mediated nuclear translocation and DNA binding of AhR, and also causes the inhibition of TCDD-induced cytochrome P450 enzyme activity.
Applications
Cell Expansion and Differentiation
Size
10 mg
Chemical Name
1-Methyl-N-[2-methyl-4-[2-(2-methylphenyl)diazenyl]phenyl-1H-pyrazole-5-carboxamide
Cell Type
Hematopoietic Stem and Progenitor Cells
Pathway
AHR
Target
AHR
Subtype
AHR Inhibitor
Area of Interest
Immunology
Limitation
Restrictions for research use only. Intended for use by laboratory professionals.
Shelf Life
Stable for 12 months from date of receipt.
Storage
Store at -20°C. Protect from prolonged exposure to light.
Molecular Weight
333.4 g/mol
Format
Solid
For Research Use Only | Not For Clinical Use
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