PharmaOnco™ Doramapimod (BIRB 796)

CAT#: ITS-0622-YT332
Product Type: Small Molecules
Product Overview
Doramapimod (BIRB 796) is highly potent p38 MAPK inhibitor, which has an IC50 for p38α=38 nM, for p38β=65 nM, for p38γ=200 nM, and for p38δ=520 nM. It also inhibits JNK2α2, B-Raf and c-Raf-1 (IC50 values are 98 nM, 83 nM and 1.4 μM, respectively).
Applications
Cell Expansion and Differentiation, Reprogramming
Size
1 mg
Chemical Name
N-[3-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N'-[4-[2-(4-morpholinyl)ethoxy]-1-naphthalenyl]urea
Cell Type
Hematopoietic Stem and Progenitor Cells, Mesenchymal Stem and Progenitor Cells, Myogenic Stem and Progenitor Cells
Pathway
p38 MAPK
Target
p38 MAPK
Subtype
p38 MAPK inhibitor
Area of Interest
Immunology
Limitation
Restrictions for research use only. Intended for use by laboratory professionals.
Shelf Life
Stable for 12 months from date of receipt.
Storage
Store at -20°C
Molecular Weight
527.7 g/mol
Format
Solid
For Research Use Only | Not For Clinical Use
Online Inquiry