PharmaOnco™ Geldanamycin

CAT#: ITS-0622-YT338
Product Type: Small Molecules
Product Overview
Geldanamycin is a benzoquinone antineoplastic antibiotic isolated from the bacterium Streptomyces hygroscopicus. Geldanamycin binds to and inhibits the cytosolic chaperone functions of heat shock protein 90 (HSP90) (Kd = 1.2 μM). HSP90 maintains the stability and functional shape of many oncogenic signaling proteins.
Applications
Cell Differentiation & Maturation
Size
1 mg
Chemical Name
9,13-Dihydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione, 9-carbamate
Target
Hsp90
Subtype
Hsp90 inhibitor
Limitation
Restrictions for research use only. Intended for use by laboratory professionals.
Shelf Life
Stable as supplied until expiry date on label.
Storage
Store at -20°C. Protect from prolonged exposure to light.
Molecular Weight
560.6 g/mol
Format
Solid
For Research Use Only | Not For Clinical Use
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