I-O™ Human Immune Genome Editing Mouse Model, Db/Kd null (CAT#: ITS-1123-HM2)

This model achieves the goal of MHC-I knockout and GvHD reduction in hu-PBL mice (mice treated with PBMCs) by silencing H2-Db/H2-Kd.

Human-specific infectious diseases; Antibody-based immune therapy; Human-specific vaccine development; Cell-based adoptiive immunity

NSG (Db/Kd null)