I-O™ Human Immune Genome Editing Mouse Model, MHC null (CAT#: ITS-1123-HM3)

This mouse model enables MHC-I/II knockout and GvHD delay in hu-PBL mice (mice treated with PBMCs) by silencing H2-DB/H2-Kd/H2-Ab1.

Human-specific infectious diseases; Antibody-based immune therapy; Human-specific vaccine development; Cell-based adoptiive immunity

NSG (MHC null)