PharmaOnco™ R848

CAT#: ITS-0622-YT339
Product Type: Small Molecules
Species: Human, Mouse
Product Overview
R-848 is a selective agonistsfor Toll-like receptor 7 (TLR7) in mouse and for TLR7 and TLR8 in human. This activation is MyD88 dependent and leads to the induction of the transcription factor NF-kB. It demonstrates potent anti-tumor and anti-viral properties and induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α.
Applications
Cell Activation and Differentiation
Size
10 mg
Chemical Name
4-amino-2-(ethoxymethyl)-a,a-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol
Species
Human, Mouse
Target
TLR7 and TLR8
Subtype
TLR7 and TLR8 Agonist
Limitation
Restrictions for research use only. Intended for use by laboratory professionals.
Shelf Life
Stable as supplied until expiry date on label.
Storage
Store at -20°C. Protect from prolonged exposure to light.
Molecular Weight
314.4 g/mol
Format
Solid
For Research Use Only | Not For Clinical Use
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