Rhod-2 AM is an organic bromide salt and a xanthene dye. It has a role as a fluorochrome. It is an acetoxymethyl (AM) ester of the red fluorescent calcium indicator rhod-2. The AM group facilitates cellular uptake and is removed by cytoplasmic esterases, resulting in intracellular accumulation of rhod-2.1,2,3 Rhod-2 AM selectively accumulates within mitochondria and, as a result, is commonly used to monitor calcium changes within this organelle. The fluorescence signal from these cells is generally measured using fluorescence microscopy. Excitation/emission maxima λ 553/577 nm.
