Product Overview
SU5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively. Additionally, SU5402 has been observed to inhibit IL-1 beta-induced MAPK activity.
Applications
Cell Maintenance
Chemical Name
2-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-4-methyl-1H-pyrrole-3-propanoic acid
Cell Type
Cancer Cells and Cell Lines, Hybridomas, Pluripotent Stem Cells
Species
Human, Mouse, Rat, Non-Human Primate, Other
Subtype
FGFR and VEGFR inhibitor
Limitation
Restrictions for research use only. Intended for use by laboratory professionals.
Datasheet