IDH2-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR42
Cell Type: CD4⁺ T Cells
RNA writers: METTL3
RNA readers: YTHDF1
RNA erasers: FTO
Enzymes: HDACs
RNA types: mRNAs
Modification: ψ
RNA editing: A to I
Short Description
This product is a IDH2-targeted RNA modification and metabolomics analysis tool based on the ψ (METTL3-YTHDF1-FTO-HDACs-phos) modification and Mevalonate pathway-mediated (hnRNPs-SAM-ATP) metabolic analysis system.
RNA writers
METTL3
RNA readers
YTHDF1
RNA erasers
FTO
Enzymes
HDACs
RNA types
mRNAs
Modification
ψ
Label
phos
RNA editing
A to I
Cell Type
CD4⁺ T Cells
Oligonucleotide
PMO
RNA Construction
mRNAs-ψ-METTL3-YTHDF1-FTO-HDACs-phos
Substrates
SAM
Cofactors
ATP
Pathway
Mevalonate pathway
Epigenetic regulator
EZH2 deficiency
Metabolic alteration
Activating branched-chain amino acidsmetabolism
Targeting diseases
Glioma
RNA-binding proteins
hnRNPs
Metabolic Reprogramming
Mevalonate pathway-hnRNPs-SAM-ATP
Target
IDH2
Alternative Names
IDH2; D2HGA2; ICD-M; IDH; IDHM; IDP; IDPM; mNADP-IDH; isocitrate dehydrogenase (NADP(+)) 2; mitochondrial; isocitrate dehydrogenase (NADP(+)) 2; IDH-2
Gene ID
3418(Human); 269951(Mouse); 361596(Rat)
UniProt ID
P48735(Human); P54071(Mouse); P56574(Rat)
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
Online Inquiry