PharmaOnco™ Beagle Canine CD14+ Cells, Purified

CAT#: IC-LX050
Product Type: OncoImmune Cells
Cell Type: CD14+ Cells
Species: Beagle Canine
Short Description
Creative Biolabs offers Beagle Canine CD14+ Cells, Purified for a variety of stimulation-dependent functional experiments to assess cytokine production, proliferation, and cytotoxicity.
Description
Beagle Canine CD14+ Cells, Purified are isolated immune cells from the blood of Beagle dogs that have been specifically purified based on the expression of the CD14 protein on their cell surface. These purified CD14+ cells can be used in research studies to investigate various aspects of canine immunity, including immune responses to infections, inflammatory diseases, and drug development.
Species character
The Beagle canine is the most commonly-used breed of dog for the study of cardiology, cancer, microbial pathogenesis, and immunology. Specifically, they have been used to study the pathogenesis of and response to Leishmania infantum, an intracellular parasite that can pose public health concerns.
Background
CD14+ cells are a good source of mature neutrophils to study their biology, in particular their functional capabilities. They are capable of secreting enzymes, as well as performing phagocytosis in response to foreign organisms.
Species
Beagle Canine
Cell Type
CD14+ Cells
Features
High quality;
High viability;
Widely applications.
Additional Donor Information
Contact us for donor specifications (Age,Gender,BMI category, smoking status, ethnicity, etc.).
Formulation
Contains Cryopreservation Medium
Cell Purity
>95%
Cell Viability
>90%
Mycoplasma Testing
The cell line has been screened using the luciferase based mycoplasma detection kit to confirm the absence of mycoplasma species.
Sterility Testing
Creative Biolabs provides sterility testing in accordance with USP and EP regulations. All of our sterility testing is performed in an isolator or clean room environments. The cell line has been screened using the membrane filtration testing methods to confirm the absence of aerobic, anaerobic and fungi microorganisms.
Genetic Stability Testing
We perform cell genetic stability studies under ICH guidelines. We can provide guidance on the appropriate testing program upon your requirements.
Application
Immunotherapy Discovery and Development
Research Use Only
Our immune cell are for research use only, not for diagnostic or therapeutic use.
Quality Control
Cultures are screened for the presence of bacteries, yeast, fungi and mycoplasma (DNA amplification). Growth media are also certified based on U.S. Public Health Service Guidelines.
Storage
Lyophilized cells should be stored in a liquid nitrogen tank (-150°C~-190°C). After thawing, cells should be immediately transferred to the appropriate culture medium and maintained under recommended culture conditions.
Handling Notes
Frozen cells should be thawed immediately upon receipt and grown according to handling procedure to ensure cell viability and proper assay performance.
Note: Do not freeze the cells upon receipt as it may result in irreversible damage to the cell line.
Disclaimer: We cannot guarantee cell viability if the cells are not thawed immediately upon receipt and grown according to handling procedure.
Warnings
Avoid multiple freeze/thaw cycles
Size
1 x 10e6 cells/vial
Status
Frozen
Note
Certain products are only available in select territories. Please contact us for more information.
For Research Use Only | Not For Clinical Use
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