PharmaOnco™ CD27/NF-kB Reporter-Jurkat Recombinant Cell Line (Human)
CAT#: IOC-02P059
Product Type: Cell Line
Organism: Human
Description
Recombinant Jurkat T cell expressing firefly luciferase gene under the control of NF-kB response elements with constitutive expression of human CD27 (also known as Tumor Necrosis Factor Receptor Superfamily Member 7, TNFRSF7, and T14, Genbank Accession #BC012160)
Applications
Screen for agonists or antagonists of CD27-CD70 signaling in a physiologically relevant cellular context Characterize T cell-mediated immune responses of CD27 and its interaction with CD70
Organism
Human
Strain Name
JURKAT
Common Name
Tumor Necrosis Factor Receptor Superfamily Member 7, TNFRSF7, T14