PharmaOnco™ CD45.1 PBMCs, C57BL/6 Mouse

CAT#: IC-LX022
Product Type: OncoImmune Cells
Cell Type: PBMC
Species: CD45.1 C57BL/6 Mouse
Short Description
Creative Biolabs offers CD45.1 PBMCs, C57BL/6 Mouse for a wide variety of immunology-based applications, including in-vitro immunoassays and ex-vivo applications.
Description
CD45.1 PBMCs refer to peripheral blood mononuclear cells from C57BL/6 mice that express the CD45.1 marker. CD45.1 is a cell surface protein that is commonly used as a marker to track cell populations in mixed chimeras or transplantation studies.
Species character
CD45.1 PBMCs come from C57BL/6 congenic mice that express the CD45.1 allele. CD45 itself is a protein tyrosine phosphatase receptor expressed on all hematopoietic cells except mature erythrocytes and platelets and is encoded by the Ptprc gene. Wild-type C57BL/6 mice normally carry the Ptprcb (CD45.2) allele while the other (congenic) strain carries the Ptprca (CD45.1) allele on the same C57BL/6 genetic background.
Background
PBMCs stand for peripheral blood mononuclear cells. These are a type of white blood cells found in the bloodstream that play a crucial role in the immune response. PBMCs are often used in research studies to investigate immune function and response to different stimuli.
Species
CD45.1 C57BL/6 Mouse
Cell Type
PBMC
Features
High quality;
High viability;
Widely applications.
Additional Donor Information
Contact us for donor specifications (Age,Gender,BMI category, smoking status, ethnicity, etc.).
Formulation
Contains Cryopreservation Medium
Cell Purity
>95%
Cell Viability
>90%
Mycoplasma Testing
The cell line has been screened using the luciferase based mycoplasma detection kit to confirm the absence of mycoplasma species.
Sterility Testing
Creative Biolabs provides sterility testing in accordance with USP and EP regulations. All of our sterility testing is performed in an isolator or clean room environments. The cell line has been screened using the membrane filtration testing methods to confirm the absence of aerobic, anaerobic and fungi microorganisms.
Genetic Stability Testing
We perform cell genetic stability studies under ICH guidelines. We can provide guidance on the appropriate testing program upon your requirements.
Application
Immunotherapy Discovery and Development
Research Use Only
Our immune cell are for research use only, not for diagnostic or therapeutic use.
Quality Control
Cultures are screened for the presence of bacteries, yeast, fungi and mycoplasma (DNA amplification). Growth media are also certified based on U.S. Public Health Service Guidelines.
Storage
Lyophilized cells should be stored in a liquid nitrogen tank (-150°C~-190°C). After thawing, cells should be immediately transferred to the appropriate culture medium and maintained under recommended culture conditions.
Handling Notes
Frozen cells should be thawed immediately upon receipt and grown according to handling procedure to ensure cell viability and proper assay performance.
Note: Do not freeze the cells upon receipt as it may result in irreversible damage to the cell line.
Disclaimer: We cannot guarantee cell viability if the cells are not thawed immediately upon receipt and grown according to handling procedure.
Warnings
Avoid multiple freeze/thaw cycles
Size
1 x 10e6 cells/vial
Status
Frozen
Note
Certain products are only available in select territories. Please contact us for more information.
For Research Use Only | Not For Clinical Use
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