PharmaOnco™ CHO-Tg(Human CD34) Stable Cell Line, Single Clone

CAT#: ITS-0822-HMM123
Product Type: Stable Cell Line
Short Description
Creative Biolabs offers CHO-Tg(Human CD34) stable cell line which the CD34 gene stably expressed in CHO cells.
Description
The CHO-Tg(Human CD34) stable cell line is a cell line derived from Chinese hamster ovary (CHO) cells that has been genetically modified to stably express the human CD34 gene. CD34 is a cell surface marker that is commonly used to identify and isolate hematopoietic stem cells and progenitor cells. By expressing CD34 on the cell surface, this stable cell line can be used as a model system for studying stem cell biology and for screening potential therapeutic agents targeting CD34-positive cells.
Features
Consistent gene expression;
Reliability and reproducibility;
Applications
Functional assay
Protein Target
CD34
Species
Human
Parental Cell Line
CHO
Background
The CD34 gene encodes a transmembrane glycoprotein that is expressed on hematopoietic stem cells and endothelial progenitor cells. It plays a crucial role in cell adhesion and migration, as well as in regulating the differentiation and proliferation of hematopoietic cells. CD34 is commonly used as a marker for identifying and isolating hematopoietic stem cells for transplantation purposes. It is also expressed on certain types of leukemia cells, and its levels can be used to monitor disease progression and response to treatment.
Unit Size
1 x 10e6 cells/vial, Frozen
Sterility Testing
Creative Biolabs provides sterility testing in accordance with USP and EP regulations. All of our sterility testing is performed in an isolator or clean room environments. The cell line has been screened using the membrane filtration testing methods to confirm the absence of aerobic, anaerobic and fungi microorganisms.
Identity Testing
Identity testing is required for newly established cell lines. Isoenzyme analysis is used to confirm the identity of the species of a cell line. Alternative methods for identity testing include DNA fingerprinting, STR analysis and karyology.
Virological Safety Testing
A broad range of viruses is susceptible to affecting human cell lines. We can provide in vivo/vitro virus safety assays by utilizing various animal systems. These viruses include: adventitious viruses, bovine viruses, human and simian viruses, porcine viruses, retrovirus and rodent viruses.
Genetic Stability Testing
We perform cell genetic stability studies under ICH guidelines. We can provide guidance on the appropriate testing program upon your requirements.
Mycoplasma Testing
The cell line has been screened using the luciferase based mycoplasma detection kit to confirm the absence of mycoplasma species.
Shipping
Dry Ice
Storage
Frozen cells should be stored in a liquid nitrogen tank (-150°C~-190°C). After thawing, cells should be immediately transferred to the appropriate culture medium and maintained under recommended culture conditions.
Handling Notes
Frozen cells should be thawed immediately upon receipt and grown according to handling procedure to ensure cell viability and proper assay performance.
Note: Do not freeze the cells upon receipt as it may result in irreversible damage to the cell line.
Disclaimer: We cannot guarantee cell viability if the cells are not thawed immediately upon receipt and grown according to handling procedure.
Warnings
Avoid multiple freeze/thaw cycles
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Quality Control
All of our stable cell lines meet the highest quality standards and have been confirmed to be pathogen-free.
For Research Use Only | Not For Clinical Use
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