PharmaOnco™ HEK293-Tg(Human CD36) Stable Cell Line, Single Clone
CAT#: ITS-0822-HMM124
Product Type: Stable Cell Line
Short Description
Creative Biolabs offers HEK293-Tg(Human CD36) stable cell line which the CD36 gene stably expressed in HEK293 cells.
Description
HEK293-Tg(Human CD36) stable cell line is a specific type of human embryonic kidney (HEK) 293 cell line that has been genetically modified to express human CD36 protein. CD36 is a cell surface receptor protein that is involved in various cellular functions, including lipid metabolism, inflammation, and immunity. These cells can be used in various research applications, including studying the role of CD36 in lipid metabolism, investigating its interaction with other proteins, and screening for potential drug targets or therapeutics.
Features
Consistent gene expression; Reliability and reproducibility;
Applications
Functional assay
Protein Target
CD36
Species
Human
Parental Cell Line
HEK293
Background
The CD36 gene is a human gene that encodes a transmembrane glycoprotein known as CD36, which is also called platelet glycoprotein IV (GPIV) or fatty acid translocase (FAT). This protein is involved in a variety of biological processes, including fatty acid metabolism, formation of certain types of blood cells, and inflammation. Additionally, CD36 is a receptor for various ligands, including oxidized low-density lipoprotein (oxLDL), thrombospondin-1, and long-chain fatty acids. Mutations or dysregulation of the CD36 gene have been associated with various diseases, including cardiovascular disease, metabolic disorders, and certain types of cancer.
Unit Size
1 x 10e6 cells/vial, Frozen
Sterility Testing
Creative Biolabs provides sterility testing in accordance with USP and EP regulations. All of our sterility testing is performed in an isolator or clean room environments. The cell line has been screened using the membrane filtration testing methods to confirm the absence of aerobic, anaerobic and fungi microorganisms.
Identity Testing
Identity testing is required for newly established cell lines. Isoenzyme analysis is used to confirm the identity of the species of a cell line. Alternative methods for identity testing include DNA fingerprinting, STR analysis and karyology.
Virological Safety Testing
A broad range of viruses is susceptible to affecting human cell lines. We can provide in vivo/vitro virus safety assays by utilizing various animal systems. These viruses include: adventitious viruses, bovine viruses, human and simian viruses, porcine viruses, retrovirus and rodent viruses.
Genetic Stability Testing
We perform cell genetic stability studies under ICH guidelines. We can provide guidance on the appropriate testing program upon your requirements.
Mycoplasma Testing
The cell line has been screened using the luciferase based mycoplasma detection kit to confirm the absence of mycoplasma species.
Shipping
Dry Ice
Storage
Frozen cells should be stored in a liquid nitrogen tank (-150°C~-190°C). After thawing, cells should be immediately transferred to the appropriate culture medium and maintained under recommended culture conditions.
Handling Notes
Frozen cells should be thawed immediately upon receipt and grown according to handling procedure to ensure cell viability and proper assay performance. Note: Do not freeze the cells upon receipt as it may result in irreversible damage to the cell line. Disclaimer: We cannot guarantee cell viability if the cells are not thawed immediately upon receipt and grown according to handling procedure.
Warnings
Avoid multiple freeze/thaw cycles
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Quality Control
All of our stable cell lines meet the highest quality standards and have been confirmed to be pathogen-free.