PharmaOnco™ Human Treg Cells, Natural

Creative Biolabs offers Human Treg Cells, Natural for studying the function of Tregs in an in vivo assays.

Natural Tregs (nTregs) are a subset of Tregs that are derived from the thymus during T cell development. They express high levels of the transcription factor Foxp3, which is essential for their suppressive function. nTregs are thought to primarily suppress immune responses to self-antigens and help prevent autoimmunity.

Regulatory T cells (Tregs) are a type of immune cell that plays a key role in preventing excessive immune responses and maintaining immune tolerance. Natural Tregs are a subset of Tregs that develop in the thymus, where they are educated to recognize self-antigens and prevent immune attacks against the body's own tissues. Human Treg cells have been the subject of intense research in recent years due to their potential therapeutic applications in various autoimmune diseases, transplant rejection, and cancer. These cells have the ability to suppress the activity of other immune cells, such as T cells and dendritic cells, thereby dampening the immune response and preventing inflammation and tissue damage.

Human

T cells

CD4 T Cells

PRMI1640

High quality;
High viability;
Widely applications.

Healthy

Contact us for donor specifications (Age,Gender,BMI category, smoking status, ethnicity, etc.).

Contains Cryopreservation Medium

> 80%

> 80%

Negative

Creative Biolabs provides sterility testing in accordance with USP and EP regulations. All of our sterility testing is performed in an isolator or clean room environments. The cell line has been screened using the membrane filtration testing methods to confirm the absence of aerobic, anaerobic and fungi microorganisms.

We perform cell genetic stability studies under ICH guidelines. We can provide guidance on the appropriate testing program upon your requirements.

All cells were collected under Institutional Review Board (IRB)-approved consent forms and protocols.

Immunotherapy Discovery and Development

Donors are negative for HIV-1, HIV-2, hepatitis B, and hepatitis C.

Stored at < -120°C once they are received.

Frozen cells should be thawed according to handling procedure or stored in a liquid nitrogen tank.

Avoid multiple freeze/thaw cycles.

1 x 10e6 cells/vial

Frozen

Certain products are only available in select territories. Please contact us for more information.