PharmaOnco™ Raji-Tg(Human TCR Activator) Stable Cell Line, Single Clone
CAT#: ITS-0822-HMM205
Product Type: Stable Cell Line
Short Description
Creative Biolabs offers Raji-Tg(Human TCR Activator) stable cell line which the TCR Activator gene stably expressed in Raji cells.
Description
Raji-Tg (Human TCR Activator) stable cell line is a cell line derived from the Raji cell line, which is a human B cell lymphoma cell line. The Raji-Tg stable cell line has been genetically modified to express a T cell receptor (TCR) activator, which can stimulate TCR signaling pathways in T cells. These stable cell lines are commonly used in research settings to study T cell activation and signal transduction pathways. They can be used to investigate the mechanisms of T cell activation, as well as to study the role of TCR signaling in immune responses and disease processes.
Features
Consistent gene expression; Reliability and reproducibility;
Applications
Functional assay
Protein Target
TCR Activator
Species
Human
Parental Cell Line
Raji
Background
TCR (T cell receptor) activators are molecules or compounds that stimulate the activity of T cells in the immune system. T cells play a crucial role in the body's immune response by identifying and attacking foreign invaders such as viruses, bacteria, and cancer cells.
Unit Size
1 x 10e6 cells/vial, Frozen
Sterility Testing
Creative Biolabs provides sterility testing in accordance with USP and EP regulations. All of our sterility testing is performed in an isolator or clean room environments. The cell line has been screened using the membrane filtration testing methods to confirm the absence of aerobic, anaerobic and fungi microorganisms.
Identity Testing
Identity testing is required for newly established cell lines. Isoenzyme analysis is used to confirm the identity of the species of a cell line. Alternative methods for identity testing include DNA fingerprinting, STR analysis and karyology.
Virological Safety Testing
A broad range of viruses is susceptible to affecting human cell lines. We can provide in vivo/vitro virus safety assays by utilizing various animal systems. These viruses include: adventitious viruses, bovine viruses, human and simian viruses, porcine viruses, retrovirus and rodent viruses.
Genetic Stability Testing
We perform cell genetic stability studies under ICH guidelines. We can provide guidance on the appropriate testing program upon your requirements.
Mycoplasma Testing
The cell line has been screened using the luciferase based mycoplasma detection kit to confirm the absence of mycoplasma species.
Shipping
Dry Ice
Storage
Frozen cells should be stored in a liquid nitrogen tank (-150°C~-190°C). After thawing, cells should be immediately transferred to the appropriate culture medium and maintained under recommended culture conditions.
Handling Notes
Frozen cells should be thawed immediately upon receipt and grown according to handling procedure to ensure cell viability and proper assay performance. Note: Do not freeze the cells upon receipt as it may result in irreversible damage to the cell line. Disclaimer: We cannot guarantee cell viability if the cells are not thawed immediately upon receipt and grown according to handling procedure.
Warnings
Avoid multiple freeze/thaw cycles
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Quality Control
All of our stable cell lines meet the highest quality standards and have been confirmed to be pathogen-free.