PharmaOnco™ THP-1-Luc Reporter Cell Line, Single Clone

Creative Biolabs offers THP-1-Luc reporter cell line which has been stably transfected with a luciferase reporter gene.

The THP-1-Luc reporter cell line is a cell line derived from human monocytic leukemia cells (THP-1 cells) that has been genetically modified to express a luciferase reporter gene. These cells are commonly used in research to study the activation of specific signaling pathways or to screen for potential therapeutic compounds.

Consistent gene expression;
Reliability and reproducibility;

Functional assay

THP-1

The Luc Reporter Cell Line is a type of cell line that has been genetically engineered to express the luciferase enzyme, which is responsible for the bioluminescent reaction that produces light. This cell line is commonly used in research applications, particularly in studying gene expression and signal transduction pathways. The ability to detect and measure the level of bioluminescence produced by these cells allows researchers to monitor various cellular processes in real-time. The Luc Reporter Cell Line is a valuable tool for studying the dynamics of gene regulation and protein expression in a variety of experimental settings.

1 x 10e6 cells/vial, Frozen

Creative Biolabs provides sterility testing in accordance with USP and EP regulations. All of our sterility testing is performed in an isolator or clean room environments. The cell line has been screened using the membrane filtration testing methods to confirm the absence of aerobic, anaerobic and fungi microorganisms.

Identity testing is required for newly established cell lines. Isoenzyme analysis is used to confirm the identity of the species of a cell line. Alternative methods for identity testing include DNA fingerprinting, STR analysis and karyology.

A broad range of viruses is susceptible to affecting human cell lines. We can provide in vivo/vitro virus safety assays by utilizing various animal systems. These viruses include: adventitious viruses, bovine viruses, human and simian viruses, porcine viruses, retrovirus and rodent viruses.

We perform cell genetic stability studies under ICH guidelines. We can provide guidance on the appropriate testing program upon your requirements.

The cell line has been screened using the luciferase based mycoplasma detection kit to confirm the absence of mycoplasma species.

Dry Ice

Frozen cells should be stored in a liquid nitrogen tank (-150°C~-190°C). After thawing, cells should be immediately transferred to the appropriate culture medium and maintained under recommended culture conditions.

Frozen cells should be thawed immediately upon receipt and grown according to handling procedure to ensure cell viability and proper assay performance.
Note: Do not freeze the cells upon receipt as it may result in irreversible damage to the cell line.
Disclaimer: We cannot guarantee cell viability if the cells are not thawed immediately upon receipt and grown according to handling procedure.

Avoid multiple freeze/thaw cycles

For research use only, not for diagnostic or therapeutic use.

All of our stable cell lines meet the highest quality standards and have been confirmed to be pathogen-free.