PharmaOnco™ Tyrosinase-Specific CD8+ T cells

CAT#: ITS-0423-LX15
Product Type: OncoImmune Cells
Cell Type: T cell population
Species: Human
Short Description
Creative Biolabs offers Tyrosinase-Specific CD8+ T cells for immunity reaserch.
Description
Tyrosinase-specific CD8+ T cells are a subset of immune cells that specifically target and recognize the enzyme tyrosinase. Tyrosinase is a key enzyme involved in the production of melanin, the pigment responsible for skin, hair, and eye color. These CD8+ T cells play a crucial role in the immune response against melanoma.
Background
Tyrosinase-specific CD8+ T cells are a subset of immune cells that specifically target and attack cells expressing the enzyme tyrosinase. Tyrosinase is an enzyme involved in the production of melanin, and is often overexpressed in melanoma cancer cells. These specialized CD8+ T cells play a crucial role in the immune response against melanoma, as they are able to recognize and kill tumor cells displaying tyrosinase on their surface. By targeting tyrosinase-expressing cells, these T cells can help to effectively eliminate melanoma tumors and prevent their spread.
Species
Human
Cell Type
T cell population
Culture medium
We recommend RPMI-1640 with 10% FBS media for our functional analysis, but that depends on the media used by customers for co-culturing experiments.
Features
High quality;
High viability;
Widely applications.
Survive Time
With proper stimulation, they will survive for about 4-5 days.
Antigen
Tyrosinase(368-376)
HLA Restricted
HLA-A*0201
Gender
Female
Donor Age
55
Donor Health
Normal
HLA-A
2:01:06
HLA-B
15:01:00
HLA-C
3:03:00
Blood Type
O+
Ethnicity
Caucasian
Anticoagulant
Acid-citrate-dextrose solution A (ACDA)
Additional Donor Information
Contact us for donor specifications (Age,Gender,BMI category, smoking status, ethnicity, etc.).
Formulation
Contains Cryopreservation Medium
Cell Purity
>80%
Cell Viability
>80%
Mycoplasma Testing
Negative
Sterility Testing
Creative Biolabs provides sterility testing in accordance with USP and EP regulations. All of our sterility testing is performed in an isolator or clean room environments. The cell line has been screened using the membrane filtration testing methods to confirm the absence of aerobic, anaerobic and fungi microorganisms.
Genetic Stability Testing
We perform cell genetic stability studies under ICH guidelines. We can provide guidance on the appropriate testing program upon your requirements.
Application
Immunotherapy Discovery and Development
Quality Control
Cultures are screened for the presence of bacteries, yeast, fungi and mycoplasma (DNA amplification). Growth media are also certified based on U.S. Public Health Service Guidelines.
Storage
Frozen cells should be stored in a liquid nitrogen tank (-150°C~-204°C).
Handling Notes
Frozen cells should be thawed according to handling procedure or stored in a liquid nitrogen tank.
Warnings
Avoid multiple freeze/thaw cycles.
Size
1 x 10e6 cells/vial
Status
Frozen
Note
Certain products are only available in select territories. Please contact us for more information.
For Research Use Only | Not For Clinical Use
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