Isochorismate Synthase-targeted RNA Modification and Metabolomics Analysis Tool
CAT#: ITS-0524-CR297
Cell Type: CD8 T Cells
RNA writers: NSUN5
RNA readers: YTHDF2
RNA erasers: TET1/2/3
Enzymes: SIRT1
RNA types: rRNA
Modification: m6A
RNA editing: C to U
Short Description
This product is a Isochorismate synthase-targeted RNA modification and metabolomics analysis tool based on the m6A (NSUN5-YTHDF2-TET1/2/3-SIRT1-spacer C18) modification and Mevalonate pathway-mediated (Matrin-3-SAM-ATP) metabolic analysis system.
RNA writers
NSUN5
RNA readers
YTHDF2
RNA erasers
TET1/2/3
Enzymes
SIRT1
RNA types
rRNA
Modification
m6A
Label
spacer C18
RNA editing
C to U
Cell Type
CD8 T Cells
Oligonucleotide
2'-OMe (cationic lipoplex)
RNA Construction
rRNA-m6A-NSUN5-YTHDF2-TET1/2/3-SIRT1-spacer C18
Substrates
SAM
Cofactors
ATP
Pathway
Mevalonate pathway
Epigenetic regulator
SIRT6 deficiency
Metabolic alteration
Upregulating glycolysis
Targeting diseases
Adrenocortical carcinoma
RNA-binding proteins
Matrin-3
Metabolic Reprogramming
Mevalonate pathway-Matrin-3-SAM-ATP
Target
Isochorismate synthase
Alternative Names
Isochorismate synthase
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.