IYD-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR206
Cell Type: M1 macrophages
RNA writers: METTL14
RNA readers: YTHDF2
RNA erasers: ALKBH5
Enzymes: MAT2A
RNA types: mRNAs
Modification: ac4C
RNA editing: A to I
Short Description
This product is a IYD-targeted RNA modification and metabolomics analysis tool based on the ac4C (METTL14-YTHDF2-ALKBH5-MAT2A-phos) modification and Glycolysis-mediated (ATAXIN-2-SAM-ATP) metabolic analysis system.
RNA writers
METTL14
RNA readers
YTHDF2
RNA erasers
ALKBH5
Enzymes
MAT2A
RNA types
mRNAs
Modification
ac4C
Label
phos
RNA editing
A to I
Cell Type
M1 macrophages
Oligonucleotide
cET, 2'-MOE
RNA Construction
mRNAs-ac4C-METTL14-YTHDF2-ALKBH5-MAT2A-phos
Substrates
SAM
Cofactors
ATP
Pathway
Glycolysis
Epigenetic regulator
ARID1A deficiency
Metabolic alteration
Inhibiting reduced glutathione synthesis
Targeting diseases
Acute Myeloid Leukemia
RNA-binding proteins
ATAXIN-2
Metabolic Reprogramming
Glycolysis-ATAXIN-2-SAM-ATP
Target
IYD
Alternative Names
IYD; iodotyrosine deiodinase; C6orf71; DEHAL1; TDH4; dJ422F24.1; IYD-1
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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