Jurkat In Vitro Ethidium Homodimer Assay (Cell Viability)

CAT#: ITS-1122-YF5692
Target Cell Organism: Human
Target Cell Name: Jurkat
Assay Type: Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Overview
This assay is to provide Jurkat-based In Vitro Ethidium Homodimer Assay (Cell Viability) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
Jurkat
Target Cell Organism
Human
Target Cell Background
The Jurkat cell line (originally called JM) was established in the mid-1970s from the peripheral blood of a 14-year-old boy with T cell leukemia. Different derivatives of the Jurkat cell line have been mutated to lack certain genes.
Related Diseases
Acute Lymphoblastic Leukemia; ALL
Research Area
Oncology
Assay Name
In Vitro Ethidium Homodimer Assay (Cell Viability)
Short Description
Jurkat-cell based In Vitro Ethidium Homodimer Assay (Cell Viability)
Assay Description
Ethidium homodimer assay is another cell viability assay, which can be used to detect dead cells. Ethidium homodimer can pene trate through the cell membrane and gives red fluorescence upon binding with DNA of dead cells.
Assay Type
Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Type Details
Uncontrolled proliferation is one of the main features of cancer cells. Cell-based in vitro assays are employed to determine whether test molecules possess direct cytotoxic/antiproliferative effects in cancer cells.
Assay Subtype
Cell Viability Assay
Assay MOA
Dye Exclusion Assays
For Research Use Only | Not For Clinical Use
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