This assay is to provide Jurkat-based In Vivo Tumorigenesis Assay to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
Jurkat
Target Cell Organism
Human
Target Cell Background
The Jurkat cell line (originally called JM) was established in the mid-1970s from the peripheral blood of a 14-year-old boy with T cell leukemia. Different derivatives of the Jurkat cell line have been mutated to lack certain genes.
Related Diseases
Acute Lymphoblastic Leukemia; ALL
Research Area
Oncology
Assay Name
In Vivo Tumorigenesis Assay
Short Description
Jurkat-cell based In Vivo Tumorigenesis Assay
Assay Description
Tumorigenicity is defined the property of a cell to form tumors when inoculated into an immunosuppressed animal model. Generally, test cells and tumor cells as positive control are administered subcutaneously into immunosuppressed nude mice. The number of animals developing tumors are compared with a positive control reference cell line.