k-ras-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR68
Cell Type: MDSCs
RNA writers: METTL14
RNA readers: YTHDF2
RNA erasers: ALKBH5
Enzymes: ACOT12
RNA types: mRNAs
Modification: m5C
RNA editing: A to I
Short Description
This product is a k-ras-targeted RNA modification and metabolomics analysis tool based on the m5C (METTL14-YTHDF2-ALKBH5-ACOT12-BHQ3) modification and Mevalonate pathway-mediated (PRPF8-SAM-ADP) metabolic analysis system.
RNA writers
METTL14
RNA readers
YTHDF2
RNA erasers
ALKBH5
Enzymes
ACOT12
RNA types
mRNAs
Modification
m5C
Label
BHQ3
RNA editing
A to I
Cell Type
MDSCs
Oligonucleotide
cET
RNA Construction
mRNAs-m5C-METTL14-YTHDF2-ALKBH5-ACOT12-BHQ3
Substrates
SAM
Cofactors
ADP
Pathway
Mevalonate pathway
Epigenetic regulator
ACLY overexpression
Metabolic alteration
Increasing the content of acetyl-CoA
Targeting diseases
Adrenocortical carcinoma
RNA-binding proteins
PRPF8
Metabolic Reprogramming
Mevalonate pathway-PRPF8-SAM-ADP
Target
k-ras
Alternative Names
KRAS; C-K-RAS; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; KI-RAS; KRAS1; KRAS2; NS; NS3; RALD; RASK2; K-ras; KRAS proto-oncogene; GTPase; c-Ki-ras2; OES; c-Ki-ras; K-Ras 2; 'C-K-RAS; K-Ras; Kirsten RAt Sarcoma virus; Kirsten Rat Sarcoma virus
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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