K562 In Vitro Trypan Blue Exclusion Assay (Cell Viability)

CAT#: ITS-1022-YF121
Target Cell Organism: Human
Target Cell Alternative Name: K-562
Target Cell Name: K562
Assay Type: Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Overview
This assay is to provide K562-based In Vitro Trypan Blue Exclusion Assay (Cell Viability) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
K562
Target Cell Organism
Human
Target Cell Background
K562 cells are of the erythroleukemia type, and the cell line is derived from a 53-year-old female chronic myelogenous leukemia patient in blast crisis. The cells are non-adherent and rounded, are positive for the bcr:abl fusion gene, and bear some proteomic resemblance to both undifferentiated granulocytes and erythrocytes.
Target Cell Alternative Name
K-562
Related Diseases
Chronic Myeloid Leukemia; CML
Research Area
Oncology
Assay Name
In Vitro Trypan Blue Exclusion Assay (Cell Viability)
Short Description
K562-cell based In Vitro Trypan Blue Exclusion Assay (Cell Viability)
Assay Description
The intact cell membranes cannot recruit these dyes into cells. Trypan blue can enter into non-viable cells, while viable cells exclude trypan blue. The trypan blue exclusion assay is a simple and commonly used assay for cell viability determination.
Assay Type
Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Type Details
Uncontrolled proliferation is one of the main features of cancer cells. Cell-based in vitro assays are employed to determine whether test molecules possess direct cytotoxic/antiproliferative effects in cancer cells.
Assay Subtype
Cell Viability Assay
Assay MOA
Dye Exclusion Assays
For Research Use Only | Not For Clinical Use
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