α-Ketoglutarate-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR323
Cell Type: DCs
RNA writers: METTL3
RNA readers: YTHDF1
RNA erasers: FTO
Enzymes: HDACs
RNA types: mRNAs
Modification: m6A
RNA editing: G to A
Short Description
This product is a α-Ketoglutarate-targeted RNA modification and metabolomics analysis tool based on the m6A (METTL3-YTHDF1-FTO-HDACs-BHQ3) modification and Glycolysis-mediated (PRPF8-SAM-α-KG) metabolic analysis system.
RNA writers
METTL3
RNA readers
YTHDF1
RNA erasers
FTO
Enzymes
HDACs
RNA types
mRNAs
Modification
m6A
Label
BHQ3
RNA editing
G to A
Cell Type
DCs
Oligonucleotide
2'-OMe
RNA Construction
mRNAs-m6A-METTL3-YTHDF1-FTO-HDACs-BHQ3
Substrates
SAM
Cofactors
α-KG
Pathway
Glycolysis
Epigenetic regulator
KMT2D deficiency
Metabolic alteration
Upregulating glycolysis
Targeting diseases
Ovarian Cancers
RNA-binding proteins
PRPF8
Metabolic Reprogramming
Glycolysis-PRPF8-SAM-α-KG
Target
α-Ketoglutarate
Alternative Names
2-oxoglutaric acid; α-Ketoglutarate
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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