L1210 In Vitro RNA Expression Analysis Assay (DNA Microarray)

This assay is to provide L1210-based In Vitro RNA Expression Analysis Assay (DNA Microarray) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.

L1210

Mouse

L1210 is a cell line exhibiting lymphoblast morphology that was isolated from the skin of an eight-month-old, female mouse with lymphocytic leukemia, developed after skin paintings with 0.2% methylcholanthrene in ether. This cell line was deposited by EM Jensen and can be used in immune system disorder research.

Lymphocytic Leukemia

Oncology

In Vitro RNA Expression Analysis Assay (DNA Microarray)

L1210-cell based In Vitro RNA Expression Analysis Assay (DNA Microarray)

DNA microarray is another technique that enables the analysis of gene expression. Fluorescent labeled cDNA (with cyanines) synthesized from a test sample is hybridized to target probes with complementary sequences attached on microarray chips and strongly bound complexes are screened after scanning optically.

Gene and Protein Expression Assays

Following transcription, primary transcript RNA is converted into mature RNA by post-transcriptional modifications. Post-transcriptional modification includes three major steps namely the addition of a 5'cap, addition of a 3'polyadenylation tail and RNA splicing. Stability of RNA has been considered as very important for gene expression and proteins at the post-transcriptional level.