LDH-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR100
Cell Type: MDSCs
RNA writers: NSUN1
RNA readers: ALYREF
RNA erasers: ALKBH1
Enzymes: HATs
RNA types: mRNAs
Modification: ac4C
RNA editing: T to C
Short Description
This product is a LDH-targeted RNA modification and metabolomics analysis tool based on the ac4C (NSUN1-ALYREF-ALKBH1-HATs-spacer C9) modification and Gluconeogenesis-mediated (MBNL-Lactyl-CoA-ATP) metabolic analysis system.
RNA writers
NSUN1
RNA readers
ALYREF
RNA erasers
ALKBH1
Enzymes
HATs
RNA types
mRNAs
Modification
ac4C
Label
spacer C9
RNA editing
T to C
Cell Type
MDSCs
Oligonucleotide
2'-OMe, 2'dT (LNP)
RNA Construction
mRNAs-ac4C-NSUN1-ALYREF-ALKBH1-HATs-spacer C9
Substrates
Lactyl-CoA
Cofactors
ATP
Pathway
Gluconeogenesis
Epigenetic regulator
ARID1A deficiency
Metabolic alteration
Inhibiting reduced glutathione synthesis
Targeting diseases
Nasopharyngeal carcinoma
RNA-binding proteins
MBNL
Metabolic Reprogramming
Gluconeogenesis-MBNL-Lactyl-CoA-ATP
Target
LDH
Alternative Names
Lactate dehydrogenase (LDH
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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