Short Description
Measures glycerol release from adipocytes (lipolysis).
Development Stage
Research-Grade Lipid Metabolism Assay Development
Description
The LipidFlux™ Adipolysis Assay Kit measures glycerol release to screen for compounds that stimulate or inhibit fat breakdown in adipocytes. This assay validates lipolytic agents and regulators of lipid mobilization, supporting the development of metabolic syndrome treatments. It provides a functional readout of adipocyte metabolism, essential for characterizing the mechanism of action of anti-diabetic drugs.
Features
Measures glycerol release; Screen for compounds that stimulate or inhibit fat breakdown in adipocytes.
Process Relevance
Lipid Mobilization Research
Application Stage
Lead Optimization
Applications
Lipid metabolism and fat cell regulation studies.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Absorbance at 570 nm, or Fluorescence Detection (Ex 530 nm / Em 585 nm)
Research Areas
Obesity; Metabolic Disease