Development Stage: Research-Grade Lipid Metabolism Assay Development
Short Description
Differentiates and quantifies cholesterol fractions (HDL vs. LDL/VLDL) with dual detection.
Brand
LipidFlux
Development Stage
Research-Grade Lipid Metabolism Assay Development
Description
The LipidFlux™ AF HDL and LDL/VLDL Assay Kit supports the detailed segmentation of cholesterol carriers, enabling researchers to evaluate the cardiovascular safety and efficacy of lipid-modulating drugs. By distinguishing between high-density and low-density lipoproteins with high specificity, this assay aids in identifying potential risks associated with drug candidates. It is an essential component of comprehensive cardiovascular risk assessment panels in pre-clinical toxicology.
Features
Advanced fractionation capabilities allow distinct quantification of lipoprotein subclasses; Essential for detailed pharmacodynamic profiling of cardiovascular drugs.
Process Relevance
Lipid Metabolism Research
Application Stage
Pre-clinical Efficacy
Applications
Comprehensive lipid metabolic profiling and cardiovascular risk assessment.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Absorbance at 570 nm, or Fluorescence Detection (Ex 530 nm / Em 585 nm)
Sample Type
Serum
Research Areas
Cardiovascular Disease; Lipid Metabolism
Size
100 tests
Data Output Type
Quantitative (Concentration)
Assay Time
Results in 60 min
LOD
OD 1 mg/dL; FL 0.2 mg/dL
Species
All Species
Storage
Store at −20 °C upon receipt to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to −20 °C storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
6 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
High-Density Lipoprotein (HDL) and Low-Density Lipoprotein (LDL) are the primary carriers of cholesterol in the blood. The balance between HDL and LDL is a fundamental predictor of cardiovascular health and the target of lipid-modulating therapies.