Short Description
Quantifies sphingomyelin in lipid extracts.
Development Stage
Research-Grade Lipid Metabolism Assay Development
Description
The LipidFlux™ Sphingomyelin Assay Kit uses enzymatic hydrolysis and fluorometric detection to validate drugs targeting sphingolipid signaling in apoptosis. This assay measures sphingomyelin levels in cell membranes and serum, supporting atherosclerosis research. It enables the investigation of lipid raft composition and the role of sphingolipids in signal transduction.
Features
Enzymatic hydrolysis and fluorometric detection; Validates drugs targeting sphingolipid signaling in apoptosis.
Process Relevance
Lipid Signaling Research
Application Stage
Discovery
Applications
Cell signaling and atherosclerosis research.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Absorbance at 570 nm or Fluorescence Detection (Ex 530 nm / Em 585 nm)
Sample Type
Serum, plasma, and other biological samples
Research Areas
Cardiovascular Disease; Cell Signaling
Datasheet