MBT-2 In Vitro Real-time Monitoring of Cell Migration Assay
CAT#: ITS-1022-YF3392
Target Cell Organism: Mouse
Target Cell Name: MBT-2
Assay Type: Cell Migration and Invasion Assays
Assay Overview
This assay is to provide MBT-2-based In Vitro Real-time Monitoring of Cell Migration Assay to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
MBT-2
Target Cell Organism
Mouse
Target Cell Background
MBT-2 cells are murine bladder cancer cells with epithelial characteristics. Their formation is induced by the administration of FANFT (N-[4-(5-nitro-2-furyl)-2-thiazolyl] formamide) to C3H/He mice.
Related Diseases
Bladder Cancer
Research Area
Oncology
Assay Name
In Vitro Real-time Monitoring of Cell Migration Assay
Short Description
MBT-2-cell based In Vitro Real-time Monitoring of Cell Migration Assay
Assay Description
Real-time monitoring assays have permitted more easy and reliable ways for the detection of cancer cell invasion and migration (real-time monitoring).
Assay Type
Cell Migration and Invasion Assays
Assay Type Details
The movement of cancer cells and formation of tumors in neighboring tissue is a sequential cascade known as invasion-metastatic cascade, which includes cancer cell invasion through extracellular matrix (ECM), intravasation into blood and colonization at sites after they exit from blood circulation. Migration and invasion are two different processes where, cell migration involves movement of cells without passing through a barrier such as ECM, whereas cell invasion involves passing through a barrier such as ECM while destroying it.