MCAT-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR368
Cell Type: M2 macrophages
RNA writers: METTL3
RNA readers: YTHDC1
RNA erasers: ALKBH5
Enzymes: ACOT12
RNA types: mRNAs
Modification: m6Am
RNA editing: T to C
Short Description
This product is a MCAT-targeted RNA modification and metabolomics analysis tool based on the m6Am (METTL3-YTHDC1-ALKBH5-ACOT12-phos) modification and Fatty acid synthesis-mediated (PRPF8-Lactyl-CoA-ATP) metabolic analysis system.
RNA writers
METTL3
RNA readers
YTHDC1
RNA erasers
ALKBH5
Enzymes
ACOT12
RNA types
mRNAs
Modification
m6Am
Label
phos
RNA editing
T to C
Cell Type
M2 macrophages
Oligonucleotide
cET
RNA Construction
mRNAs-m6Am-METTL3-YTHDC1-ALKBH5-ACOT12-phos
Substrates
Lactyl-CoA
Cofactors
ATP
Pathway
Fatty acid synthesis
Epigenetic regulator
SMARCA4 deficiency
Metabolic alteration
Upregulating oxidative phosphorylation
Targeting diseases
Acute Myeloid Leukemia
RNA-binding proteins
PRPF8
Metabolic Reprogramming
Fatty acid synthesis-PRPF8-Lactyl-CoA-ATP
Target
MCAT
Alternative Names
MCAT; FASN2C; MCT; MT; NET62; fabD; malonyl-CoA-acyl carrier protein transacylase; MCT1
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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