MCF7 In Vitro Telomere Length Analysis Assay (Senescence)

This assay is to provide MCF7-based In Vitro Telomere Length Analysis Assay (Senescence) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.

MCF7

Human

MCF-7 is a breast cancer cell line isolated in 1970 from a 69-year-old White woman. MCF-7 is the acronym of Michigan Cancer Foundation-7, referring to the institute in Detroit where the cell line was established in 1973 by Herbert Soule and co-workers. MCF7 are epithelial cells isolated from the breast tissue of a 69-year-old, White, female patient with metastatic adenocarcinoma. Use these cells in your breast cancer research.

MCF-7

Breast Adenocarcinoma

Oncology

In Vitro Telomere Length Analysis Assay (Senescence)

MCF7-cell based In Vitro Telomere Length Analysis Assay (Senescence)

For the analysis of telomere length, terminal restriction fragment analysis technique has been the commonly used technique for a long time.

Cellular Senescence in Cancer Assays

Cell senescence is described as an irreversible physiological event of cell growth arrest, which is known to be caused by alterations of telomeres, oxidative stress, DNA damage and some oncogenes. Inhibition of the program of senescence is one of the main features of tumor cells and it has been reported that cancer cells can be induced to undergo senescence by chemo- and radiotherapies and genetic alterations. Telomeres help to prevent uncontrolled cell proliferation and the absence of telomeres results in aneuploidy and cell death.

Telomere Length Analysis Assay