MCI-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR300
Cell Type: M1 macrophages
RNA writers: DNMT2
RNA readers: ALYREF
RNA erasers: ALKBH1
Enzymes: HATs
RNA types: rRNA
Modification: ac4C
RNA editing: T to C
Short Description
This product is a MCI-targeted RNA modification and metabolomics analysis tool based on the ac4C (DNMT2-ALYREF-ALKBH1-HATs-Biotin) modification and Gluconeogenesis-mediated (FUS-Lactyl-CoA-ATP) metabolic analysis system.
RNA writers
DNMT2
RNA readers
ALYREF
RNA erasers
ALKBH1
Enzymes
HATs
RNA types
rRNA
Modification
ac4C
Label
Biotin
RNA editing
T to C
Cell Type
M1 macrophages
Oligonucleotide
2'-MOE, GalNAc
RNA Construction
rRNA-ac4C-DNMT2-ALYREF-ALKBH1-HATs-Biotin
Substrates
Lactyl-CoA
Cofactors
ATP
Pathway
Gluconeogenesis
Epigenetic regulator
ARID1A deficiency
Metabolic alteration
Inhibiting reduced glutathione synthesis
Targeting diseases
Renal and Bladder Cancers
RNA-binding proteins
FUS
Metabolic Reprogramming
Gluconeogenesis-FUS-Lactyl-CoA-ATP
Target
MCI
Alternative Names
CatB; MCI; MLE; 2;5-dihydro-5-oxofuran-2-acetate lyase
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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