MDH1-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR49
Cell Type: CD8 T Cells
RNA writers: METTL14
RNA readers: YTHDF2
RNA erasers: ALKBH5
Enzymes: HDACs
RNA types: mRNAs
Modification: ac4C
RNA editing: C to U
Short Description
This product is a MDH1-targeted RNA modification and metabolomics analysis tool based on the ac4C (METTL14-YTHDF2-ALKBH5-HDACs-phos) modification and Mevalonate pathway-mediated (α-synuclein-Acetyl-CoA-α-KG) metabolic analysis system.
RNA writers
METTL14
RNA readers
YTHDF2
RNA erasers
ALKBH5
Enzymes
HDACs
RNA types
mRNAs
Modification
ac4C
Label
phos
RNA editing
C to U
Cell Type
CD8 T Cells
Oligonucleotide
LNA
RNA Construction
mRNAs-ac4C-METTL14-YTHDF2-ALKBH5-HDACs-phos
Substrates
Acetyl-CoA
Cofactors
α-KG
Pathway
Mevalonate pathway
Epigenetic regulator
SMARCA4 deficiency
Metabolic alteration
Upregulating oxidative phosphorylation
Targeting diseases
Breast Cancer
RNA-binding proteins
α-synuclein
Metabolic Reprogramming
Mevalonate pathway-α-synuclein-Acetyl-CoA-α-KG
Target
MDH1
Alternative Names
MDH1; HEL-S-32; MDH-s; MDHA; MGC:1375; MOR2; malate dehydrogenase 1; EIEE88; DEE88; KAR
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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