ME2-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR52
Cell Type: MDSCs
RNA writers: METTL1
RNA readers: eIF4E; CBC
RNA erasers: /
Enzymes: KMTs
RNA types: mRNAs
Modification: m6A
RNA editing: A to I
Short Description
This product is a ME2-targeted RNA modification and metabolomics analysis tool based on the m6A (METTL1-eIF4E; CBC-KMTs-spacer C18) modification and Mevalonate pathway-mediated (hnRNPs-SAM-NAD+) metabolic analysis system.
RNA writers
METTL1
RNA readers
eIF4E; CBC
RNA erasers
/
Enzymes
KMTs
RNA types
mRNAs
Modification
m6A
Label
spacer C18
RNA editing
A to I
Cell Type
MDSCs
Oligonucleotide
2'-OMe, 2'dT (LNP)
RNA Construction
mRNAs-m6A-METTL1-eIF4E; CBC-KMTs-spacer C18
Substrates
SAM
Cofactors
NAD+
Pathway
Mevalonate pathway
Epigenetic regulator
G9A overexpression
Metabolic alteration
Upregulating serine-glycine biosyntheticpathway
Targeting diseases
Acute Myeloid Leukemia
RNA-binding proteins
hnRNPs
Metabolic Reprogramming
Mevalonate pathway-hnRNPs-SAM-NAD+
Target
ME2
Alternative Names
ME2; ODS1; malic enzyme 2
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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